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Using a segment of rat Fak (PTK2) to screen an adult human brain cDNA library, Bongiorno-Borbone et al. (2005) cloned DLGAP3, which they called SAPAP3. The...
DLGAP4 is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with...
DLG7 is a kinetochore protein that stabilizes microtubules in vicinity of chromosomes. DLG7 controls spindle dynamics, promotes interkinetochore tension and...
DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types,...
The Dlk1 gene appears to function as a regulator of adipogenesis. Adult Dlk1-deficient mice are obese, but adipose tissue still develops in transgenic mice...
DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during...
DLL3 encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a...
DLL4 is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a...
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its...
Dystrophin is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding...
Myotonic dystrophy protein kinase is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small...
DMRT1 is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an...
Raymond et al. (1999) sought other genes with DM domains within the minimal sex reversal region of 9p. Using a degenerate PCR strategy, they isolated a cDNA...
DMRTA1, Belongs to the DMRT family. Contains 1 DM DNA-binding domain. Expressed in liver, kidney, pancreas, prostate and weakly detected in testis and...
DMRTA2 is involved in gonadal differentiation. The gene is part of five novel human DM genes that map to three well-defined regions of chromosomes 1, 9, and...
In humans, the DMRT genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the...
DMRTC2 belongs to the DMRT family. Contains 1 DM DNA-binding domain. Expressed in testis and pancreas. May be involved in sexual development. Recent advances...
DMTF1 encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains...
By EST database searching for sequences showing homology to Drosophila DmX and by use of primers designed for RT-PCR from human placental mRNA, Kraemer et...
DMXL2 shares significant homology with DMXL1. RT-PCR ELISA detected moderate expression in brain, lung, liver, kidney, testis, and ovary. Expression was low...
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