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DHX8 is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box...
DHX9 encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of...
DIABLO encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis,...
The product of DIAPH2 belongs to the diaphanous subfamily of the formin homology family of proteins. DIAPH2 may play a role in the development and normal...
DIAPH3 encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement...
DICER1 encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded...
Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis...
The protein encoded by DIP2A may be involved in axon patterning in the central nervous system. DIP2A is not highly expressed. Several transcript variants...
DIP2C encodes a member of the disco-interacting protein homolog 2 family. DIP2C shares strong similarity with a Drosophila protein which interacts with the...
DIRAS1 (DIRAS Family GTPase 1) is a Protein Coding gene. GO annotations related to DIRAS1 include GTP binding and mitogen-activated protein kinase binding....
DIRAS2 (DIRAS Family GTPase 2) is a Protein Coding gene. GO annotations related to DIRAS2 include GTP binding. An important paralog of DIRAS2 is DIRAS1....
ARHI contains a highly conserved GTP-binding domain, a putative effector domain distinct from that of RAS and RAP proteins, and a C-terminal membrane...
DIRC2 has a conserved motif that is shared with the major facilitator superfamily of transporters between membrane-spanning domains 2 and 3, and a...
Podolski et al. (2001) described a reciprocal, balanced, constitutional chromosome translocation, t(2;3)(q33;q21), that is associated with familial clear...
By randomly sequencing clones obtained from a size-fractionated brain cDNA library, Nagase et al. (1999) cloned DIS3, which they designated KIAA1008. The...
Dis3L is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the cytoplasm of eukaryotic cells. DIS3L belongs to...
The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3' to 5' exoribonucleases. The complex is involved in...
Disrupted-in-Schizophrenia 1 or DISC1 is a protein with a wide array of functions. It participates in cell growth, movement, axonal growth and transport,...
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized...
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized...
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