Human Protein delta homolog 2 (DLK2) ELISA Kit

The Dlk1 gene appears to function as a regulator of adipogenesis. Adult Dlk1-deficient mice are obese, but adipose tissue still develops in transgenic mice overexpressing an Fc-dlk1 fusion protein, and neither type of genetically modified mice displays serious abnormalities. EGFL9, encoding for a protein whose structural features are virtually identical to those of dlk1, suggesting it may function in a similar way. As dlk1 does, the protein encoded by EGFL9/Dlk2 affects adipogenesis of 3T3-L1 preadipocytes and mesenchymal C3H10T1/2 cells; however, it does so in an opposite way to that of dlk1. In addition, expression levels of both genes appear to be inversely correlated in both cell lines. Moreover, enforced changes in the expression of one gene affect the expression levels of the other.

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SPECIFICATIONS

Catalog Number

KTE62019

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

65989

Accession

Q6UY11

Additional Info

Human Protein delta homolog 2 (DLK2) ELISA Kit has high sensitivity and excellent specificity for detection of Human DLK2. No significant cross-reactivity or interference between Human DLK2 and analogues was observed.