Human Doublesex- and mab-3-related transcription factor B1 (DMRTB1) ELISA Kit

In humans, the DMRT genes encode a large family of transcription factors that are related to the Drosophila doublesex proteins. Expressed primarily in the gonads, the DMRT proteins contain cysteine-rich DNA-binding motifs and are thought to play an important role in sexual development. DMRTB1 (Doublesex- and mab-3-related transcription factor B1) is a 342 amino acid protein that contains one DM DNA-binding domain and belongs to the DMRT family. Localized to the nucleus and expressed in the testis, DMRTB1 may participate in developmental processes and, via its DM domain, may bind to DNA and regulate transcription. DMRTB1 belongs to the DMRT family. Contains 1 DM DNA-binding domain.