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DNA topoisomerase 2-beta (TOP2B) controls topological states of DNA by transient breakage and subsequent rejoining of DNA strands. TOP2B makes double-strand...
Tumor necrosis factor ligand superfamily member 6 (Fas ligand, FasL) is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal...
Caspase-9 is known to be involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. Binding of caspase-9 to...
Caspase-7 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. Caspase-7 cleaves and activates sterol...
Caspase-6 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. Caspase-6 cleaves poly(ADP-ribose)...
Caspase-4 is involved in the activation cascade of caspases responsible for apoptosis e, Xenopus/Amphibian,ecution. Caspase-4 cleaves caspase-1. Caspase-4...
Inhibitor of CAD (ICAD) is an inhibitor of the caspase-activated DNase (DFF40). ICAD is a heterodimer of DFFA and DFFB. ICAD is phosphorylated upon DNA...
Lysyl o, Xenopus/Amphibian,idase homolog 1 (LO, Xenopus/Amphibian,L1) is active on elastin and collagen substrates. LO, Xenopus/Amphibian,L1 is e,...
Lysyl o, Xenopus/Amphibian,idase homolog 1 (LO, Xenopus/Amphibian,L1) is an enzyme which is active on elastin and collagen. LO, Xenopus/Amphibian,L1 is e,...
Protein kinase C eta type (PKC eta) is a calcium-independent,Porcinehospholipid-dependent, serine- and threonine-specific enzyme. PKC eta is activated by...
The CD54 antigen (ICAM-1) engagement promotes the assembly of endothelial apical cups through SGEF and RHOG activation during leukocyte trans-endothelial...
Eukaryotic translation initiation factor 4E transporter (EIF4ENIF1) is a nucleoplasmic shuttling protein. EIF4ENIF1 mediates the nuclear import of EIF4E by a...
mRNA-decapping enzyme 2 (DCP2) is necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. DCP2 plays a role...
Piwi-like protein 4 (PIWIL4) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is...
The 3-phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates PKB/AKT,PorcineKA,PorcineKC-zeta, RPS6KA1 and RPS6KB1 playing a general...
Caspase-8 is the most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death....
p53 acts as a tumor suppressor in many tumor types by inducing growth arrest or apoptosis. P53 is also involved in cell cycle regulation as transactivator...
Interleukin-6R binds to IL6 with low affinity, but does not transduce a signal. A soluble IL-6R is produced by both naive and memory CD4 T cells upon TCR...
Alpha-enolase (ENO1) is a multifunctional enzyme that, as well as its role in glycolysis,Porcinelays a part in various processes such as growth control,...
MICAL-like protein 2 (MICALL2) is a cytosolic protein that interacts with neuronal ple, Xenopus/Amphibian,in A (Ple, Xenopus/Amphibian,A) receptors. Members...
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