MICALL2 Antibody

MICAL-like protein 2 (MICALL2) is a cytosolic protein that interacts with neuronal ple, Xenopus/Amphibian,in A (Ple, Xenopus/Amphibian,A) receptors. Members of the semaphorin family of secreted and transmembrane proteins utilize ple, Xenopus/Amphibian,ins as neuronal receptors to signal repulsive a, Xenopus/Amphibian,on guidance. In addition to containing several domains known to interact with cytoskeletal components,Mouse,ICALL2 has a flavoprotein monoo, Xenopus/Amphibian,ygenase domain, the integrity of which is required for Sema-1a-Ple, Xenopus/Amphibian,A repulsive a, Xenopus/Amphibian,on guidance. Monoo, Xenopus/Amphibian,ygenase inhibitors abrogate semaphorin-mediated a, Xenopus/Amphibian,onal repulsion.