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PIWIL4 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 252207

PIWIL4 Antibody

Piwi-like protein 4 (PIWIL4) plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. PIWIL4 acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming comple, Xenopus/Amphibian,es composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. PIWIL4 directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements.

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SPECIFICATIONS

Catalog Number

252207

Size

0.1 mg

Applications

IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 0.5% BSA with 0.09% sodium azide. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PIWIL4.

Isotype

Rabbit Ig

Accession

Q7Z3Z4

Additional Info

Piwi-like protein 4; PIWIL4; HIWI2; PIWI

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