Mouse Leukocyte cell derived chemotaxin 1 (LECT1) ELISA Kit

LECT1 is a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. LECT1 expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone.

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SPECIFICATIONS

Catalog Number

KTE71190

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

16840

Accession

Q9Z1F6

Additional Info

Mouse Leukocyte cell derived chemotaxin 1 (LECT1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse LECT1. No significant cross-reactivity or interference between Mouse LECT1 and analogues was observed.