Mouse Klotho (KL) ELISA Kit

Klotho is a type-I membrane protein that is related to ?-glucuronidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss.\nKlotho is a transmembrane protein that, in addition to other effects, provides some control over the sensitivity of the organism to insulin and appears to be involved in aging. Its discovery was documented in 1997 by Kuro-o et al. The name of the gene comes from Klotho or Clotho, one of the Moirae, or Fates, in Greek mythology.

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SPECIFICATIONS

Catalog Number

KTE71209

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

16591

Accession

O35082

Additional Info

Mouse Klotho (KL) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse KL. No significant cross-reactivity or interference between Mouse KL and analogues was observed.