SPATS2 (Spermatogenesis Associated Serine Rich 2) is a Protein Coding gene. GO annotations related to SPATS2 include poly(A) RNA binding. An important...
SPC24 (SPC24, NDC80 Kinetochore Complex Component) is a Protein Coding gene. Among its related pathways are Mitotic Metaphase and Anaphase and Cell Cycle,...
Spc25 encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for...
The protein encoded by SPG11 is a potential transmembrane protein that is phosphorylated upon DNA damage. Defects in SPG11 are a cause of spastic paraplegia...
SPG20 encodes a protein that contains a MIT (Microtubule Interacting and Trafficking molecule) domain. This protein may be involved in endosomal trafficking,...
The protein encoded by SPG21 binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction...
SPG7 encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles...
Sphk1 encodes a kinase that phosphorylates sphingosine into sphingosine-1-phosphate, which is involved in cell differentiation, motility, and apoptosis. The...
SPHKAP (SPHK1 Interactor, AKAP Domain Containing) is a Protein Coding gene. GO annotations related to this gene include protein kinase A binding. An...
SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a...
The protein encoded by SPIB is a transcriptional activator that binds to the PU-box (5'-GAGGAA-3') and acts as a lymphoid-specific enhancer. Four transcript...
The protein encoded by SPIC regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells.
SPIN4 (Spindlin Family Member 4) is a Protein Coding gene. An important paralog of this gene is SPIN1.
The NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by TH1L...
The protein encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence...
TGFBRAP1 encodes a protein that binds to transforming growth factor-beta (TGF-beta) receptors and plays a role in TGF-beta signaling. The encoded protein...
This locus TGFBR3 encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions...
TGFBR2 encodes a member of the serine/threonine protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that...
Tgfbr1 encodes a member of the transforming growth factor beta (TGF-beta) receptor family of proteins. These proteins comprise one component of the TGF-beta...
TGF-? is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active...