Human Matrix metalloproteinase 7 (MMP-7) ELISA Kit

MMP7, also known as Matrilysin, is the smallest member of the MMP-family, it is a zinc-dependent metalloproteinase and is overexpressed in colon cancer and many other human cancers. MMP7 is a secreted matrix metalloproteinase, which contributes to angiogenesis by breaking down basement membranes. Matrix Metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components.\nMMP7 is responsible for hydrolyzing proteoglycans and ECM glycoproteins. It is expressed in normal cells, specifically glandular epithelial cells. MMP7, is thought to play an important role in the early steps of tumor progression. Expression of MMP2, MMP7 and MMP11 is greater in pancreatic carcinoma than in normal pancreas.

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SPECIFICATIONS

Catalog Number

KTE62228

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Hum

Gene Id

4316

Accession

P09237

Additional Info

Human Matrix metalloproteinase 7 (MMP-7) ELISA Kit has high sensitivity and excellent specificity for detection of Human MMP7. No significant cross-reactivity or interference between Human MMP7 and analogues was observed.