Catalogue number: |
SMC-181C |
Reactivities: |
Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Western Blot |
Size: |
25ug |
Clone: |
SP-6 |
Accession: |
NP_004594.1 |
Gene: |
6804 |
Swiss prot: |
Q16623 |
Dilutions: |
1:1000 (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Neurobiology |
Certificate of analysis: |
1 ug/mL of SMC-181 was sufficient for detection of Syntaxin in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Syntaxins are a family of membrane integrated Q-SNARE proteins participating in exocytosis (1). They possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. This SNARE domain binds to synaptobrevin and SNAP-2 |
Alternative names: |
HPC1, P35 1, STX1, STX1A, STX1B, STX2, STX3 |
References: |
1. Bennett M.K., et al. (1993) Cell. 74(5): 863-873. 2. Walter A.M., Wiederhold K., Bruns D., Fasshaurer D. and Sorensen J.B. (2010) J Cell BIol. 188(3): 401-413.
3. Honma S., Taki K., Lei S., and Wakisaka S. (2010) Anat Rec. Epub.
4. Aalto M.K., Ronne H. |