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Products HIF2 alpha, EP190b
| Catalogue number: | SMC-185D |
| Reactivities: | Human |
| Hosts: | Mouse |
| Applications: | ELISA, Immunocytochemistry, Immunohistochemistry, Western Blot |
| Size: | 100ug |
| Clone: | EP190B |
| Accession: | NP_001421.4 |
| Gene: | 2034 |
| Swiss prot: | Q99814 |
| Dilutions: | 1:100-1:500 (WB) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Oxidative Stress/Cell Signaling |
| Certificate of analysis: | 1 ug/mL of SMC-185 was sufficient for detection of HIF2(A) in 20ug of CoCl2-induced Hela cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Members of the hypoxia-inducible factor (HIF) family of transcription factors regulate the cellular response to hypoxia (1). HIF2-Alpha is involved in catecholamine homeostasis, vascular remodeling, physiological angiogenesis and adipogenesis. It is overe |
| Alternative names: | ECYT4, EPAS1, HIF2alpha, HIF1 Alpha like factor, HLF, Hypoxia inducible factor 2 alpha, MOP2, PASD2 |
| References: | 1. Kim W.Y., et al. (2009) J Clin Invest. 119(8): 2160-2170. 2. Favier J., Lapointe S., Maliba R. and Sirois M.G. (2007) BMC Cancer. 7:139. 3. Imtiyaz H.Z., et al. (2010) J Clin Invest. 120(8): 2699-2714. |
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