Catalogue number: |
SMC-183D |
Reactivities: |
Human |
Hosts: |
Mouse |
Applications: |
ELISA, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
Pab 1801 |
Accession: |
NP_000537.3 |
Gene: |
7157 |
Swiss prot: |
Q3LRW3 |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Cell Signaling |
Certificate of analysis: |
1 ug/mL of SMC-183 was sufficient for detection of p53 in 10ug of HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
The p53 protein (tumor protein 53 or TP53) is a DNA-binding cell cycle-regulating transcription
factor that governs cell division and the fine
balance between cell death and cell survival (1).
P53 plays a critical role in tumor suppression and
hence it is |
Alternative names: |
P53, LFS1, TRP53, FLJ92943, TP53 |
References: |
1. Georescu C.V., Saftoiu A., Georgescu C.C., Ciurea R. and Ciurea T. (2007) J Gastrointestin
Liver Dis. 16(2): 133-9.
2. Strachan T., et al. (1999) Human Molecular
Genetics 2. Ch. 18: Cancer Genetics.
3. Hansen J.E., et al. (2007) Cancer Research
67: 176 |