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Products HIF1 alpha, ESEE122
| Catalogue number: | SMC-184D |
| Reactivities: | Human, Mouse, Rat, Bovine |
| Hosts: | Mouse |
| Applications: | ELISA, Immunocytochemistry, Immunohistochemistry |
| Size: | 100ug |
| Clone: | ESEE122 |
| Accession: | NP_034561.2 |
| Gene: | 15251 |
| Swiss prot: | Q61221 |
| Dilutions: | 1:1000-1:8000 (IHC), 8-21ug/mL (ICC/IF) |
| Form: | Protein G purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Oxidative Stress/Cell Signaling |
| Certificate of analysis: | 1 ug/mL of SMC-184 was sufficient for detection of HIF1(A) in 20ug of CoCl2-induced Hela cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor that plays a critical role in the cellular response of hypoxia (1). The HIF1 complex consists of two subunits, HIF1-Alpha and HIF1-Beta, which are basic helix-loop-helix proteins of |
| Alternative names: | ARNT interacting protein, HIF1A, Hypoxia inducible factor 1 alpha, MOP1, PASD8 |
| References: | 1. Sharp F.R. and Bernaudin M. (2004) Nat Rev Neurosci 5, 437-48. 2. Wang G.L., et al. (1995) Proc Natl Acad Sci U S A 92, 5510-4. 3. Jaakkola P., et al. (2001) Science 292, 468-72. 4. Maxwell P.H., et al. (1999) Nature 399, 271-5. 5. Fukuda R., et al. (2 |
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