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Sodium-Iodide Symporter, 14F

Cat no: SMC-390D

Sodium-Iodide Symporter, 14F

Apparent mol. wt of 97kD, non-glycosylated version at\n68kD. Other minor bands\nassociated with hNIS at160\nkDa, and degradation products\nat ~30 kDa, and ~15kDa.

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SPECIFICATIONS

Catalog Number

SMC-390D

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Form

Protein G purified

Clone

14F

Gene Id

6528

Isotype

IgG1

Accession

NP_000444.1

Dilutions

1:1000 (WB)

References

1. Dai G., Levy O., Carrasco N. (1996) Nature. 379(6564): 458-460.\n2. Snabik P.A., et al. (1997) Endocrin. 138(8): 3555-3558.\n3. Dohan O., et al. (2007) Proc Natl Acad Sci USA. 104(51):\n20250-20255.

Swiss Prot

Q92911

Storage Temp

-20

Concentration

1mg/mL

Research Area

Ion Channels

Shipping Temp

Blue Ice or 4

Storage Buffer

PBS pH7.4, 50% glycerol

Alternative Names

NIS, SLC5A5, solute carrier family 5, Na (+)I(-) cotransporter

Scientific Background

The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral\nmembrane into thyroid epithelial cells (1, 2). This is\nimportant step in the process of iodide organificaton and\nthe formation of triiodothyronine and

Certificate Of Analysis

1 ug/mL of SMC-390 was sufficient for detection of hNIS in 20 ug of transfected COS-7 cell membrane lysate by ECL\nimmunoblot analysis using Goat anti-mouse IgG:HRP as\nthe secondary antibody.

Applications

ELISA, IP, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, ICC, IHC

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov

More info

Applications

ELISA, ICC, IHC

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov, Can, Ch/Bird, GP, Ham, Prc, Rabbit, Sheep

More info

Applications

ELISA, ICC, IHC, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov, Can, Ch/Bird, GP, Ham, Prc, Rabbit, Sheep

More info

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Ch/Bird, GP, Prc

More info

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