Catalogue number: |
SMC-329D |
Reactivities: |
Human, Mouse |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug |
Clone: |
S22-21 |
Accession: |
NP_113939.2 |
Gene: |
78957 |
Swiss prot: |
Q9WV48 |
Dilutions: |
1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Scaffolds |
Certificate of analysis: |
1 ug/mL of SMC-329 was sufficient for detection of Shank1 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of
membrane and cytoplasmic proteins (3). Shank1 specifically
might be relevant to human autism spectrum disorders, due
to its differential role in sp |
Alternative names: |
Spank1, Sstrip, Shank1a, Shank1 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Sheng M., and Kim E. (2000) Journal of Cell Science. 113:
1851-1856.
4. Hung A.Y., et al. (2008) J Neurosci. 28(7): 16 |