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SHANK1, S22-21

SHANK1, S22-21

Cat no: SMC-329D


Supplier: StressMarq Biosciences Inc.
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Detects ~190-220 kDa (alternative splice variants). No cross-reactivity against Shank2 or Shank3.
Catalogue number: SMC-329D
Reactivities: Human, Mouse
Hosts: Mouse
Applications: Immunohistochemistry, Western Blot
Size: 100ug
Clone: S22-21
Accession: NP_113939.2
Gene: 78957
Swiss prot: Q9WV48
Dilutions: 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Scaffolds
Certificate of analysis: 1 ug/mL of SMC-329 was sufficient for detection of Shank1 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins (3). Shank1 specifically might be relevant to human autism spectrum disorders, due to its differential role in sp
Alternative names: Spank1, Sstrip, Shank1a, Shank1
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Sheng M., and Kim E. (2000) Journal of Cell Science. 113: 1851-1856. 4. Hung A.Y., et al. (2008) J Neurosci. 28(7): 16