Catalogue number: |
SMC-177D |
Hosts: |
Mouse |
Applications: |
ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
1D4 |
Accession: |
NP_000530.1 |
Gene: |
6010 |
Swiss prot: |
P08100 |
Dilutions: |
1:1000 (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Signaling, GTPase |
Certificate of analysis: |
1 ug/mL of SMC-177 was sufficient for detection of rhodopsin in 10ug of rat eye lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Rhodopsin consists of the protein moiety opsin and a reversibly covalently bound cofactor, retinal. Opsin, a bundle of seven membrane embedded alpha-helices, binds retinal, a photoreactive chromophore, in a central pocket (2, 3). In addition to being the |
Alternative names: |
OPN2, opsd, opsin 2, opsin 2 rod pigment, opsin2, RHO, RP4, MGC138309, Retinitis Pigmentosa 4 |
References: |
1. Molday R.S., Hicks D., and Molday L. (1987) Invest Ophthalmol Vis Sci. 28: 50-61.
2. Ridge K.D., Lee S.S.J., and Abdulaev N.G. (1996) J of Biol Chem. 271: 7860-7867.
3. Matsuyama T., Yamashita T., Imai H. and Shichida Y. (2009) J Biol Chem. Manuscript |