Catalogue number: |
SMC-156C |
Reactivities: |
Human, Chicken/Bird, Guinea Pig, Rabbit |
Hosts: |
Mouse |
Applications: |
ELISA, Immunoprecipitation, Western Blot |
Size: |
25ug |
Clone: |
JJ6 |
Accession: |
NP_006592.3 |
Gene: |
10728 |
Swiss prot: |
Q15185 |
Dilutions: |
1:2000 (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Heat Shock |
Certificate of analysis: |
0.5ug/mL of SMC-156 was sufficient for detection of p23 in 20ug of heat shocked cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
p23 is a highly conserved ubiquitous protein, known to have an important function as a cochaperone for the
hsp90 chaperoning system (1). Studies have revealed that
p23 is a small protein (18 to 25 kDa) with a simple
structure (2, 3). p23 does not have any |
Alternative names: |
co chaperone p23, PTGES3, TEBP, telomerase binding protein p23, unactive progesterone receptor 23kDa |
References: |
1. Johnson J.L., Beito T. G., Krco C.J. & Toft D.O. (1994) Mol Cell Biol 14: 1956-63.
2. Weikl T., Abelmann K. & Buchner J. (1999) J Mol Biol
293: 685-91.
3. Weaver A.J., Sullivan W.P., Felts S.J., Owen B.A. &
Toft, D.O. (2000) J Biol Chem 275: 23045-52.
|