Catalogue number: |
SMC-337D |
Reactivities: |
Human, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S59-36 |
Accession: |
NP_036706.1 |
Gene: |
24410 |
Swiss prot: |
Q00960 |
Dilutions: |
1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG2B |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-337 was sufficient for detection of NR2B in 10ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
NR2B containing receptors have been implicated in synaptic plasticity, memory formation and pain modulation (3). Studies suggest that the NR2B subunit of glutamate receptors may be potential targets for relieving pain; NR2B may be a probable target for an |
Alternative names: |
NMDAR2B, hNR3, MGC142180, glutamate receptor subunit epsilon-2, NR3 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Zhuo M. (2009) Mol Brain. 2(1): 4
4. Gurwitz D, and Weizman A. (2002) Drug Discovery Today, 7(7): 403-406. |