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Products NAV1.8 , S134-12
| Catalogue number: | SMC-342D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunocytochemistry, Immunohistochemistry, Western Blot |
| Size: | 100ug |
| Clone: | S134-12 |
| Accession: | NP_058943.1 |
| Gene: | 29571 |
| Swiss prot: | Q62968 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG2a |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Ion Channels |
| Certificate of analysis: | 1 ug/mL of SMC-342 was sufficient for detection of Nav1.8 in 10ug of COS cell lysate transiently expressing Nav1.8 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Nav1.8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with th |
| Alternative names: | PN3, Na(V)1.8, Scn10a |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Dray A. (2008) Br. J. Anaesth. 101(1): 48-58. 4. Dray A., Read S.J (2007) Arthritis Res. Ther. 9(3): 212. 5. Samuels M.E |
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