NAV1.7, S68-6

Detects ~230kDa. No cross-reactivity against other Nav channels.

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SPECIFICATIONS

Catalog Number

SMC-314D

Size

100ug

Applications

ICC, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat

Form

Protein G Purified

Clone

S68-6

Gene Id

6335

Isotype

IgG1

Accession

NP_002968.1

Dilutions

1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)

References

1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.\n2. www.iochannels.org\n3. Dray A. (2008) Br. J. Anaesth. 101(1): 48-58.\n4. Dray A., Read S.J (2007) Arthritis Res. Ther. 9(3): 212.\n5. Samuels M.E

Swiss Prot

Q15858

Storage Temp

-20

Concentration

1mg/mL

Research Area

Channels and Transporters

Shipping Temp

Blue Ice or 4

Storage Buffer

PBS pH7.4, 50% glycerol

Alternative Names

ETHA, hNE Na, NE NA, PN1, SCN9A, voltage gated sodium channel subunit alpha Nav1, peripheral sodium channel 1, neuroendocrine sodium channel

Scientific Background

Nav1.7 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials\nand is thus important for electrical signaling by most\nexcitable cells. Therapeutically, the association of pain\ninsensitivity with th

Certificate Of Analysis

1 ug/mL of SMC-314 was sufficient for detection of Nav1.7 in 10ug of HEK-293 cell lysate transiently expressing Nav1.7 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.