Catalogue number: |
SMC-178C |
Reactivities: |
Human |
Hosts: |
Mouse |
Applications: |
Western Blot |
Size: |
25ug |
Clone: |
EP10 |
Accession: |
NP_003170.1 |
Gene: |
6855 |
Swiss prot: |
P08247 |
Dilutions: |
1.0ug/mL (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Neurobiology |
Certificate of analysis: |
1 ug/mL of SMC-178 was sufficient for detection of Synaptophysin in 10ug of human brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Synaptophysin is a synaptic vesicle glycoprotein with four transmembrane domains weighing 38kDa (1). It is present in neuroendocrine cells and in virtually all neurons in the brain and spinal cord that participate in synaptic transmission. It acts as a ma |
Alternative names: |
SYPH, Sypl, Syn p38 |
References: |
1. Johnston P.A., et al. (1989) J Biol Chem. 264: 1268-1273. 2. Thiele C., et al. (2000) Nat Cell Biol. 2: 42-49
3. Valtorta F., et al. (2004) Bioessays 26: 445-453.
4. Tarpey P.S., et al. (2009) Nat Genet. 41(5): 535-543. |