Catalogue number: |
SMC-353D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S17-70 |
Accession: |
NP_034728 |
Gene: |
16498 |
Swiss prot: |
P62482 |
Dilutions: |
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-353 was sufficient for detection of Kv(B)2 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Depolarization-activated postassium channels (Kv) play a major role in shaping the electrical signals in the nervous
system (3). KvBeta2, otherwise known as potassium voltagegated
channel, shaker-related subfamily beta member 2, is
encoded by the KCNAB2 g |
Alternative names: |
KCNA2B, SCNAB2, KCNK2, Kv Beta2, HKvbeta2, AKR6A5 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Planck-Gesellschaft M., et al. (1996) J. Physiol. 493(3):
625-633.
4. Tipparaju S.M., Barski O.A., Srivastava S and Bhat |