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Products KvBeta1.2, S47-42
| Catalogue number: | SMC-362D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S47-42 |
| Accession: | NP_003462. |
| Gene: | 7881 |
| Swiss prot: | Q14722 |
| Dilutions: | 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Ion Channels |
| Certificate of analysis: | 1ug/mL of SMC-362 was sufficient for detection of Kv(B)1.2 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Depolarization-activated potassium channels (Kv) play a major role in shaping the electrical signals in the nervous system (3). KvBeta isoforms form a heteromultimeric complex with alpha subunits and modulate the activity of the pore-forming alpha subuni |
| Alternative names: | KCNAB1, KCNA1B |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Planck-Gesellschaft M., et al. (1996) J. Physiol. 493(3): 625-633. 4. Entrez Gene |
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