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Kv2.1, S89-34

Kv2.1, S89-34

Cat no: SMC-380D


Supplier: StressMarq Biosciences Inc.
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Detects ~105-125kDa (varies with cell background due to phosphorylation). No crossreactivity to rat Kv2.2.
Catalogue number: SMC-380D
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: S89-34
Accession: NP_037318
Gene: 25736
Swiss prot: P15387
Dilutions: 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Ion Channels
Certificate of analysis: 1ug/mL of SMC-380 was sufficient for detection of Kv2.1 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional
Alternative names: Shab, Kv2.1, DRK1PC, Kcr1-1, Kcnb1
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Bocksteins E., et al. (2009) Am J Physiol. 296:C1271-C1278. 4. Ishikawa K, Tanaka M, Black J.A., and Wasman S.G. (1999)