Catalogue number: |
SMC-354D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation |
Size: |
100ug |
Clone: |
S19-36 |
Accession: |
NP_038596.1 |
Gene: |
16494 |
Swiss prot: |
Q61923 |
Dilutions: |
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
Form: |
PEG purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
img/mL |
Isotype: |
IgG3 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-354 was sufficient for detection of Kv1.6 in 20ug of rat brain lysate by colorimetric
immunoblot analysis using goat anti-mouse IgG:HRP
as the secondary antibody. |
Scientific background: |
Voltage gated channels are tetrameters composed of four subunit
consists of six transmembrane segments with
cytoplasmic NH2 and COOH-termini. Members of the KV1-4
subfamilies generate functional K+ channels in a
homotetrameric configuration (3). |
Alternative names: |
HBK2, KCNA6 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Bocksteins E., et al. (2009) Am J Physiol. 296:C1271-1278. |