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Products Kv1.5 K+ channel, S7-45
| Catalogue number: | SMC-349D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S7-45 |
| Accession: | NP_037104.1 |
| Gene: | 25470 |
| Swiss prot: | P19024 |
| Dilutions: | 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Ion Channels |
| Certificate of analysis: | 1ug/mL of SMC-349 was sufficient for detection of Kv1.5 in 20ug of transiently transfected COS cell lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit consists of six transmembrane segments with cytoplasmic NH2 and COOH-termini. Members of the KV1- KV4 subfamilies generate functional |
| Alternative names: | HCK1, HK2, HPCN1, KV1, KCNA5, PCN1 |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Bocksteins E., et al. (2009) Am J Physiol. 296:C1271-C1278. |
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