Catalogue number: |
SMC-351D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S13-31 |
Accession: |
NP_037103.1 |
Gene: |
25469 |
Swiss prot: |
P15385 |
Dilutions: |
1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
1ug/mL of SMC-351 was sufficient for detection of Kv1.4 in 20ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Voltage gated channels are tetrameters composed of four alpha-subunits arranged around a central pore. Each alphasubunit
consists of six transmembrane segments with
cytoplasmic NH2 and COOH-termini. Members of the KV1-
KV4 subfamilies generate functional |
Alternative names: |
HBK4, HK1, HPCN2, HUKII, KCNA4, KCNA8, PCN2 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Bocksteins E., et al. (2009) Am J Physiol. 296:C1271-C1278. |