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Products KIR2.3, S25-35
| Catalogue number: | SMC-312D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Western Blot |
| Size: | 100ug |
| Clone: | S25-35 |
| Accession: | NP_032453 |
| Gene: | 16520 |
| Swiss prot: | P52189 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Channels and Transporters |
| Certificate of analysis: | 1 ug/mL of SMC-312 was sufficient for detection of Kir2.3 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they |
| Alternative names: | IRK3, HIR, HIRK2, HRK1, KCNJ4, potassium inwardly rectifying channel subfamily J member 4 |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Zobel C., et al. (2003) J Physiol. 550: 365-372. 4. Panama B.K., McLerie M., and Lopatin A.N. (2007) Am J Physiol Heart |
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