Catalogue number: |
SMC-310D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Western Blot |
Size: |
100ug |
Clone: |
S112B-14 |
Accession: |
NP_032451 |
Gene: |
16518 |
Swiss prot: |
P35561 |
Dilutions: |
1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
Form: |
Protein G purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Channels and Transporters |
Certificate of analysis: |
1 ug/mL of SMC-310 was sufficient for detection of Kir2.1 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
The Kir2.1 inward-rectifier potassium ion channel is encoded by the KCNJ2 gene. A defect in this gene is associated with
Andersen-Tawil syndrome (3). |
Alternative names: |
HHBIRK1, HHIRK1, HIRK 1, IRK1, KCNJ2, LQT7, SQT3, potassium inwardly rectifying channel J2 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Donaldson M.R., Yoon G., Fu Y.H., Ptacek L.J. (2004).
Ann. Med. 36 Suppl 1: 92 |