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Products KCNQ4, S43-6
| Catalogue number: | SMC-309D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunocytochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S43-6 |
| Accession: | NP_004691.2 |
| Gene: | 9132 |
| Swiss prot: | P56696 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Channels and Transporters |
| Certificate of analysis: | 1 ug/mL of SMC-309 was sufficient for detection of KCNQ4 in 10ug of COS-1 cell lysate transiently expressing KCNQ4 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Specifically, the protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability (3), particularly in sensory cells of the cochlea (4). The current generated by this channel is inh |
| Alternative names: | DFNA2, KQT like 4, Kv7.4, voltage gated potassium channel subunit Kv7.4 |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Hernandez C.C., Zaiko O., Tolstykh G.P., Shapiro M.S. (2008) J Physiol. 586(7): 1811-1821. 4. Kharkovets T., et al. (200 |
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