Catalogue number: |
SMC-308D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S26A-23 |
Accession: |
NP_004509.2 |
Gene: |
3785 |
Swiss prot: |
O43526 |
Dilutions: |
1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Channels and Transporters |
Certificate of analysis: |
1 ug/mL of SMC-308 was sufficient for detection of KCNQ2 in 10ug of COS-1 cell lysate transiently expressing KCNQ2 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Specifically, Kv7.2 (KvLQT2) is a potassium channel protein coded for by the gene KCNQ2. It is associated with benign
familial neonatal convulsions (3). |
Alternative names: |
BFNC, EBN1, ENB1, HNSPC, KCNA11, KQT like 2, KV7.2, KVEBN1. KvLQT2, voltage gated potassium channel subunit Kv7.2 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Wuttke T.V., et al. (2008) J Physiol. 586(2): 545-555. |