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Products Hsp90 complex
| Catalogue number: | SMC-109A |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunoprecipitation |
| Size: | 50ug |
| Clone: | 8D3 |
| Accession: | NP_031381.2 |
| Gene: | 3326 |
| Swiss prot: | P08238 |
| Form: | PEG Purified |
| Storage buffer: | PBS, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgM |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Heat Shock |
| Certificate of analysis: | Goat anti-mouse IgM was used to bind 25 ul of protein G-Sepharose. SMC-109 IgM from 0.5 ml of high speed supernatant medium was loaded onto the IgG resin and incubated with 100 ul of rabbit reticulocyte lysate for 30 min. at 30C. After washing (4X1 ml), b |
| Scientific background: | Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of |
| References: | 1. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 2. Pearl H, et al. (2001) Adv Protein Chem 59:157-186. 3. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 4. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 5. Pratt W, Toft D. (1997) Endoc |
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