Hsp90(A)(B)

Cat no: SMC-135C

Supplier: StressMarq Biosciences Inc.

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Detects 90kD proteins corresponding to the molecular mass of hsp90 (A) or (B).

Catalogue number:	SMC-135C
Reactivities:	Human, Rat
Hosts:	Mouse
Applications:	ELISA, Immunohistochemistry, Western Blot
Size:	25ug
Clone:	Hyb-K41220A
Accession:	NP_031381.2, NP_001017963.2
Gene:	3326, 3320
Swiss prot:	P08238, P07900
Dilutions:	1ug/ml was sufficient for detection of hsp90(A)(B) by Western Blot in 20ug of HeLa lysate.
Form:	Protein G Purified
Storage buffer:	PBS pH7.2, 50% glycerol
Concentration:	1mg/mL
Isotype:	IgG2a
Shipping temp:	Blue Ice or 4
Storage temp:	-20
Research area:	Heat Shock
Certificate of analysis:	1ug/ml was sufficient for detection of Hsp90(A)(B) in 20ug of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary.
Scientific background:	HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms (A) and (B), which share 85% sequence amino acid homology. The two isoforms of Hsp90 are expressed in the cytosolic compartment (1). Des
Alternative names:	Hsp86, Hsp89A, Hsp90AA1, Hsp90Alpha, HspC1, HSPCA, HspCAL3, Hsp84, Hsp90B, HspC2, HspCB, D6S182, FLJ26984
References:	1. Nemoto, T. et al. (1997) J.Biol Chem. 272, 26179-26187. 2. Minami, Y, et al. (1991), J.Biol Chem. 266, 10099-10103. 3. Arlander SJH, et al. (2003) J Biol Chem 278, 52572-52577. 4. Pearl H, et al. (2001) Adv Protein Chem 59,157-186. 5. Neckers L, et al.