Hsp70/Hsc70

Detects ~72 and ~73kDa proteins corresponding to the molecular mass of inducible Hsp and Hsc on SDS PAGE immunoblots.

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SPECIFICATIONS

Catalog Number

SMC-106A

Size

50ug

Applications

IHC, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov, Can, Ch/Bird, GP, Ham, Rabbit, Sheep

Form

Protein G Purified

Clone

BB70

Gene Id

423504

Isotype

IgG2a

Accession

NP_001006686.1

Dilutions

1ug/ml was sufficient for detection of hsp70/Hsc70 in 20ug of HeLa lysate.

References

1. Zho J. (1998) Cell 94 : 471-480. 2. Boorstein W. R., Ziegelhoffer T. & Craig E. A. (1993) J.\nMol. Evol.38 (1): 1-17.\n3. Rothman J. (1989) Cell 59: 591 -601.\n4. DeLuca-Flaherty et al. (1990) Cell 62: 875-887.\n5. Bork P., Sander C. & Valencia A. (1992) P

Swiss Prot

P08106

Storage Temp

-20

Concentration

1mg/mL

Research Area

Heat Shock

Shipping Temp

Blue Ice or 4

Storage Buffer

PBS pH7.2, 50% glycerol

Alternative Names

HSC54, Hsc70, HSC71, Hsp70 1, Hsp701/Hsp70 2, Hsp70.1, Hsp71, Hsp72, Hsp73, HSPA1, HSPA10, HSPA1A, HSPA1B, LAP1, NIP71

Scientific Background

Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic r

Certificate Of Analysis

1 ug/mL of SMC-106 was sufficient for detection of Hsp70 and Hsc70 in 20ug of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.