Catalogue number: |
SMC-187D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
ELISA, Immunohistochemistry, Western Blot |
Size: |
100ug |
Clone: |
3C12-H11 |
Accession: |
NP_055180.2 |
Gene: |
26354 |
Swiss prot: |
Q9UJY2 |
Dilutions: |
1:2000 (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 Kappa |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Heat Shock |
Certificate of analysis: |
1 ug/mL of SMC-187 was sufficient for detection of Hsp22 in 20 ug of whole rat tissue extract by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
Hsp22 (HSPB8) is a 196-amino acid protein that is a member of the small heat shock protein super-family and
the human protein is most closely related to Hsp27.
Similar to most other sHSPs, Hsp22 is predominately
transcribed in skeletal muscle and heart, a |
Alternative names: |
Alpha crystallin C chain, CMT2L, CRYAC, DHMN2, H11, Heat shock 22kDa protein 8, HMN2, HSB8, HspB8 |
References: |
1.Kappe G., et al. (2001) Biochem Biophys Acta 1520: 1-6.
2.Benndorf R., et al. (2001) J Biol Chem 276: 26753-
26761.
3.Sun X., et al. (2004) J Biol Chem 279: 2394-2402.
4.Kim M.V., et al. (2004) Biochem Biophys Res Commun
325: 649-652.
5. Wilhelmus M.M., |