Catalogue number: |
SMC-105B |
Reactivities: |
Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Guinea Pig, Hamster, Horse, Porcine, Rabbit, Sheep |
Hosts: |
Rat |
Applications: |
Immunoprecipitation, Western Blot |
Size: |
200ug |
Clone: |
9G10 |
Accession: |
NP_003290.1 |
Gene: |
7184 |
Swiss prot: |
P14625 |
Dilutions: |
0.5ug/ml was sufficient for detection of Grp94 in 20ug of HeLa lysate. |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.2, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG2a |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Heat Shock |
Certificate of analysis: |
0.5 ug/mL of SMC-105 was sufficient for detection of Grp94 in 20ug of heat shocked HeLa cell lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody. |
Scientific background: |
Grp94 (glucose regulated protein 94, gp96) is a constitutively expressed endoplasmic reticulum (ER)
lumenal protein that is up-regulated in response to
cellular stress such as heat shock, oxidative stress or
glucose depletion. Grp94 is thought to play a r |
Alternative names: |
HSP90B1, GP96, TRA1, ECGP |
References: |
1. Rudolph R.W., and Bedows E. (1997) J Biol Chem 272: 3125-3128.
2. Srivastava P.K., et al. (1994) Immunogenetics. 39(2):93-
98.
3. Mazzarella R.A., and Green M. (1987) J Biol Chem 262:
8875-8883.
4. Kang, H.S. and Welch W.J. (1991) J Biol Chem 266(9):
5 |