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Products Grp75
| Catalogue number: | SMC-133D |
| Reactivities: | Human, Mouse |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S52A-42 |
| Accession: | NP_004125.3 |
| Gene: | 3313 |
| Swiss prot: | P38646 |
| Dilutions: | 1:1000 (colorimetric) (WB) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.2, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Heat Shock |
| Certificate of analysis: | 1ug/ml was sufficient for detection of Grp75 in 10ug of heat shock HeLa lysate by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary. |
| Scientific background: | Grp75, also known as mortalin, is a member of Hsp70 family of chaperone proteins that is not heat inducible (1, 2). Grp75 is actually induced under conditions of low glucose and other nutritional and environmental stresses. Grp75 resides primarily in the |
| Alternative names: | Hsc74, Hsp74, HspA9, Hspa9a, HspA9B, Mortalin 2, MOT2, PBP74 |
| References: | 1. Kaul S.C., et al. (1993) Biochem Biophys Res Commun. 193: 348-355. 2. Wadhwa R., et al. (1993) J Biol Chem 268: 6615-6621. 3. Schneider H.C., et al. (1994) Nature 371: 768-774. 4. Manning-Krieg U.C., et al. (1991) EMBO J. 10: 3273-3280. 5. Wadhwa R., e |
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