Catalogue number: |
SMC-345D |
Reactivities: |
Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunocytochemistry, Western Blot |
Size: |
100ug |
Clone: |
S151-3 |
Accession: |
NP_058985.1 |
Gene: |
29689 |
Swiss prot: |
P18506 |
Dilutions: |
1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG2a |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Ion Channels |
Certificate of analysis: |
2ug/mL of SMC-345 was sufficient for detection of Delta1 GABA-A receptor in 10ug of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features (3). GABA-A receptors are the major fast inhibitory neurotransmitter gat |
Alternative names: |
GABAA-RD, Gabrd, MGC105467 |
References: |
1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA.
2. www.iochannels.org
3. Bracamontes J.R. and Steinbach J.H. (2008) J Bio Chem. 283: 26128-26136.
4. Macdonald R.L., Olsen R.W. (1993) Annu Rev N |