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Products FKBP52
| Catalogue number: | SMC-139D |
| Reactivities: | Human, Mouse, Rat, Canine, Hamster |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | Hi52C |
| Accession: | NP_002005.1 |
| Gene: | 2288 |
| Swiss prot: | Q02790 |
| Dilutions: | 1:2000 (WB), 5ug with 10-20uL Protein A beads (IP), 1:250 (IHC) |
| Form: | Protein G Purified |
| Storage buffer: | PBS, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Heat Shock |
| Certificate of analysis: | 0.5ug/ml was sufficient for detection of FKBP52 in 20ug total protein using WB by colorimetric immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary. |
| Scientific background: | Hsp90 is crucial to cellular signaling by its regulation of the folding, activity, and stability of a wide range of client proteins. These client protein complexes may also contain one or more cochaperones (1). One class of Hsp90-binding cochaperone is co |
| Alternative names: | FK506 binding protein 4, FKBP4, FKBP59, HBI, Hsp56, p52, p59, PPIase, Rotamase, T cell FK506 binding protein |
| References: | 1. Cheung-Flynn J., Roberts P.J., Riggs D.L., and Smith D.F. (2003) J. Biol. Chem. 278(19): 17388-17394. 2. Davies T.H., Ning Y.N., and Sanchez E.R. (2002) J Biol. Chem. 277 (7): 4597-4600. 3. Wu, B. et al. (2004) Proc. Natl. Acad. Sci. USA. 101(22): 8348 |
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