Catalogue number: |
SMC-138D |
Reactivities: |
Human, Mouse, Rat, Canine, Hamster, Rabbit |
Hosts: |
Mouse |
Applications: |
Western Blot |
Size: |
100ug |
Clone: |
Hi51B |
Accession: |
NP_001139247.1 |
Gene: |
2289 |
Swiss prot: |
Q13451 |
Dilutions: |
1:2000 (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Heat Shock |
Certificate of analysis: |
A 1:2000 dilution was sufficient for detection of FKBP51 in ~50ug total protein using WB anaylsis. |
Scientific background: |
Hsp90 is crucial to cellular signaling by its regulation of the folding, activity, and stability of a wide range of client proteins. These client protein complexes may also contain one or more cochaperones (1). One class of Hsp90-binding cochaperone is co |
Alternative names: |
AIG6, FK506 binding protein 5, FKBP5, FKBP54, Hsp90 binding immunophilin, p54, Pplase, Ptg10, Rotamase, T cekk FK506 binding protein antibody |
References: |
1. Cheung-Flynn J., Roberts P.J., Riggs D.L., and Smith D.F.(2003) J. Biol. Chem. 278(19): 17388-17394.
2. Davies T.H., Ning Y.N., and Sanchez E.R. (2002) J Biol. Chem. 277 (7): 4597-4600.
3. Wu B. et al. (2004) Proc. Natl. Acad. Sci. USA. 101(22): 8348-8 |