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Products FKBP51
| Catalogue number: | SMC-138C |
| Reactivities: | Human, Mouse, Rat, Canine, Hamster, Rabbit |
| Hosts: | Mouse |
| Applications: | Western Blot |
| Size: | 25ug |
| Clone: | Hi51B |
| Accession: | NP_001139247.1 |
| Gene: | 2289 |
| Swiss prot: | Q13451 |
| Dilutions: | 1:2000 (WB) |
| Form: | Protein G Purified |
| Storage buffer: | PBS, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Heat Shock |
| Certificate of analysis: | A 1:2000 dilution was sufficient for detection of FKBP51 in ~50ug total protein using WB anaylsis. |
| Scientific background: | Hsp90 is crucial to cellular signaling by its regulation of the folding, activity, and stability of a wide range of client proteins. These client protein complexes may also contain one or more cochaperones (1). One class of Hsp90-binding cochaperone is co |
| Alternative names: | AIG6, FK506 binding protein 5, FKBP5, FKBP54, Hsp90 binding immunophilin, p54, Pplase, Ptg10, Rotamase, T cekk FK506 binding protein antibody |
| References: | 1. Cheung-Flynn J., Roberts P.J., Riggs D.L., and Smith D.F.(2003) J. Biol. Chem. 278(19): 17388-17394. 2. Davies T.H., Ning Y.N., and Sanchez E.R. (2002) J Biol. Chem. 277 (7): 4597-4600. 3. Wu B. et al. (2004) Proc. Natl. Acad. Sci. USA. 101(22): 8348-8 |
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