Catalogue number: | SMC-192D |
Reactivities: | Human |
Hosts: | Mouse |
Applications: | Immunohistochemistry, Western Blot |
Size: | 100ug |
Clone: | P2B1 |
Accession: | NP_149418.3 |
Gene: | 22947 |
Dilutions: | 1:1000 (WB) |
Form: | Protein G Purified |
Storage buffer: | PBS pH7.4, 50% glycerol |
Concentration: | 1mg/mL |
Isotype: | IgG1 |
Shipping temp: | Blue Ice or 4 |
Storage temp: | -20 |
Research area: | Transcription Factor |
Certificate of analysis: | 1ug/mL of SMC-192 was sufficient for detection of DUX4 in 20ug of HeLa cell lysate by ECL immunoblot analysis using goat anti-mouse IgG: HRP as teh secondary. |
Scientific background: | DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function |
Alternative names: | double homeobox 4, DUX10 |
References: | 1. Entrez Gene: |