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CNGA1/3, S36-12

CNGA1/3, S36-12

Cat no: SMC-389D


Supplier: StressMarq Biosciences Inc.
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Detects ~80kDa (size will vary depending on species and isoform). Recognizes both rod and cone alpha subunits.
Catalogue number: SMC-389D
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: S36-12
Dilutions: 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: IgG1
Shipping temp: Blue Ice or 4
Storage temp: -2
Research area: Ion Channels
Certificate of analysis: 1ug/mL of SMC-389 was sufficient for detection of CNGA1/3 in 20ug of zebra fish lysate by colorimetric immunoblot analysis using goat antimouse IgG:HRP as the secondary antibody.
Scientific background: CNGA1 and 3 belong to the cyclic nucleotide-gated channel family (CNG). They produce the primary electrical signal in photoreceptors upon absorption of a photon. These channels also generate the electrical signal in olfactory receptors, and are expressed
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Burns M.E. and Baylor D.A. (2001) Annu Rev Neurosci. 24: 779-805. 4. Zufall F., and Munger S.D. (2001) Trends Neurosci.