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Products CAVBETA2 , S8b-1
| Catalogue number: | SMC-332D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S8B-1 |
| Accession: | NP_446303 |
| Gene: | 116600 |
| Swiss prot: | Q8VGC3 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Ion Channels |
| Certificate of analysis: | 1 ug/mL of SMC-332 was sufficient for detection of Cav(B)2 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody |
| Scientific background: | Cav Beat subunits are involved in the transport of the pore forming alpha1 subunit to the plasma membrane (3). They also shield an ER Retention signal on the alpha1 subunit, thereby guiding the pore-forming subunit to the target membrane (4, 5). They also |
| Alternative names: | Cacnlb2, cacnb2 |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Dolphin A.C. (2003) J Bioenerg. Biomembr. 35: 599-620. 4. Bichet D., et al. (2000) Neuron. 25: 177-190. 5. Xie M., et al |
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