Quick Search
Products CAV1.2, S57-46
| Catalogue number: | SMC-300D |
| Reactivities: | Human, Mouse, Rat |
| Hosts: | Mouse |
| Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 100ug |
| Clone: | S57-46 |
| Accession: | NP_001129994.1 |
| Gene: | 100144322 |
| Swiss prot: | P15381 |
| Dilutions: | 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF) |
| Form: | Protein G Purified |
| Storage buffer: | PBS pH7.4, 50% glycerol |
| Concentration: | 1mg/mL |
| Isotype: | IgG1 |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Channels and Transporters |
| Certificate of analysis: | 1 ug/mL of SMC-300 was sufficient for detection of Cav1.2 in 10ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
| Scientific background: | Specifially, Cav1.2 is a cardiac L-type calcium channel, and is important for excitation and contraction of the heart (3). It may be associated with a variant of Long QT syndrome called Timothy's syndrome (4, 5) and also with Brugada syndrome. Some refere |
| Alternative names: | CACH3, CACN4, CACNA 1D, CACNL1A2, voltage dependent L type calcium channel subunit alpha 1D |
| References: | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.:Sunderland, MA USA. 2. www.iochannels.org 3. Splawski I., et al. (2004) Cell. 119 (1): 19-31. 4. Krey J.F., and Dolmetsch R. (2009) Biophysical. 96 (3): 221a-222a. 5. |
Get the Best Promotions
