Catalogue number: |
SMC-366D |
Reactivities: |
Human, Mouse, Rat |
Hosts: |
Mouse |
Applications: |
Immunohistochemistry, Immunoprecipitation, Western Blot |
Size: |
100ug |
Clone: |
S56A-50 |
Accession: |
NP_071520.1 |
Gene: |
29647 |
Swiss prot: |
Q62915 |
Dilutions: |
1:1000 (WB) |
Form: |
Protein G Purified |
Storage buffer: |
PBS pH7.4, 50% glycerol |
Concentration: |
1mg/mL |
Isotype: |
IgG1 |
Shipping temp: |
Blue Ice or 4 |
Storage temp: |
-20 |
Research area: |
Scaffolds |
Certificate of analysis: |
1 ug/mL of SMC-366 was sufficient for detection of CASK in 20 ug of rat brain tissue extract by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. |
Scientific background: |
CASK (calmodulin sensitive kinase) is a ~112kDa member of the membrane associated quanylate kinase (MAGUK)
protein family. It is an adaptor protein with a
calcium/calmodulin-dependent protein kinase domain, a
SH3 domain, aguanylate kinase homology domain |
References: |
1. Hata Y., et al. (1996). J Neurosci. 16: 2488-2494.
2. Hsueh Y.P., et al. (2000) Nature. 404: 298-302.
3. Laverty H.G., and Wilson J.B. (1998) Genomics. 53: 29-41.
4. Ojeh N., Pekovic V., Jahoda C., and Maatta A. (2008) J
Cell Sci. 121(16): 2705-2717. |