BK channel BETA3, S40B-18

Cat no: SMC-330D

Supplier: StressMarq Biosciences Inc.

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Detects ~32 kDa. No cross-reactivity against BKBeta1, BKBeta1, BKBeta3b or BKBeta4.

Catalogue number:	SMC-330D
Reactivities:	Human, Mouse, Rat
Hosts:	Mouse
Applications:	Immunohistochemistry, Immunoprecipitation, Western Blot
Size:	100ug
Clone:	S40B-18
Accession:	NP_055222.3
Gene:	27094
Swiss prot:	Q9NPA1
Dilutions:	1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF)
Form:	Protein G Purified
Storage buffer:	PBS pH7.4, 50% glycerol
Concentration:	1mg/mL
Isotype:	IgG1
Shipping temp:	Blue Ice or 4
Storage temp:	-20
Research area:	Ion Channels
Certificate of analysis:	1 ug/mL of SMC-330 was sufficient for detection of BK Beta3a in 10ug of COS cell (lysate) transiently transfected with BKbeta3a by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background:	BK channels contribute to electrical impulses, proper signal transmission of information and regulation of neurotransmitter release (3). A gain of function mutation in the pore-forming alpha subunit of the BK channel was linked to human neurological disea
Alternative names:	HBETA3, KCNMB2, KCNMBL, BKBeta3, KCNMB3
References:	1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Wulf-Johansson H., et al. (2009) Brain Res. 1292: 1- 13. 4. Lee U.S., and Cui J. (2009) J Physiol. 587(7): 1481- 1489.