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Products Aha1
| Catalogue number: | SMC-172C |
| Reactivities: | Human, Mouse |
| Hosts: | Rat |
| Applications: | ELISA, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Size: | 25ug |
| Clone: | 25F2.D9 |
| Accession: | NP_666148.1 |
| Gene: | 217737 |
| Swiss prot: | Q8BK64 |
| Form: | Protein G Purified |
| Storage buffer: | 0.02M potassium phosphate, 0.15M sodium chloride, ph&.2 |
| Concentration: | 1.2mg/mL |
| Isotype: | IgG2a Kappa |
| Shipping temp: | Blue Ice or 4 |
| Storage temp: | -20 |
| Research area: | Heat Shock |
| Certificate of analysis: | 1 ug/mL of SMC-172 was sufficient for detection of Aha1 in 10ug of rat tissue lysate by colorimetric immunoblot analysis using Goat anti-rat IgG:HRP as the secondary antibody. |
| Scientific background: | Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also |
| Alternative names: | Ahsa1, p38, HspC322, C14orf3 |
| References: | Hainzl O., Lapina M.C., Buchner J., Richter K. (2009) J Biol Chem. Epub. 2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt.3): 789-796. 3. Lotz G.P., Brychzy A., Heinz S., Obermann W.M. (2008) J Cell Sci. 121(pt.5): 717-723. 4. Holmes J.L., Sh |
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